Journal of AI, Software & Web Technologies
Volume 1, Issue 1
2026 · pp. 1–429 · 42 articles
- Volume
- 1
- Issue
- 1
- Published
- 2026
- Pages
- 1–429
- Articles
- 42
- Sections
- 1
- ISSN
- Journal
- J. AI Softw. Web Technol.
In this issue
Research Articles
- Review
A Review on Polyherbal Nanoparticles with Combined Effect of Metal Nanoparticle-Properties and Applications
Sivaranajani Balakrishnan, Karthikeyan Ramadoss, Geetha Govindarajulu
pp. 1–9 · DOI: 10.5530/pres.20270180 · Published Oct-Dec 2027
The current review summarizes the processes, characteristics and uses of Nanoparticles (NPs) sourced from polyherbal formulations, such as fullerenes, metal NPs, ceramic NPs and polymeric NPs. In order to make different …
- Review
Phytochemical and Pharmacological Potential of Pithecellobium dulce: A Review
Sivasubramanian Piramanayagam, Sakthi Puvisha Muthu, Elango Gopalan, Cibi Veeramani, Shalini Balraj, Ragavi Sivakumar, Pushparam Asaithambi
pp. 10–20 · DOI: 10.5530/pres.20270005 · Published Oct-Dec 2027
Pithecellobium dulce (Roxb.) Benth is a medicinal plant that is commonly used in traditional medicine and its phytochemical profile has shown to contain numerous bioactive compounds which are characterized by the presenc…
- Review
Targeted Neurotherapeutics: A Review of Bacopa monnieri Delivery Strategies for Neurodegeneration
Divya Kanojiya, Suzain Garasiya, Ghanshyam Parmar
pp. 21–33 · DOI: 10.5530/pres.20270063 · Published Oct-Dec 2027
Neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Autism lead to Central Nervous System (CNS) degeneration, impairing both cognitive and motor functions. With the rising prevalence of thes…
- Review
Natural Products in Dental Care (2010-2026): A Narrative Review of Efficacy, Clinical Utility, and Research Gaps
pp. 34–30 · DOI: 10.5530/pres.20270176 · Published Jan-Mar 2027
Plant byproducts have been used as supplements owing to their antimicrobial, antioxidant, and anti-inflammatory properties. They also help treat and prevent many dental problems. However, the use of herbal treatments pre…
- Article
Phytochemical Profiling and Antioxidant Assessment of Methanolic Leaf Extract of Ziziphus oenoplia from Badangi Village, Odisha
Swetasri Priyadarshini, Sabir Kumar Behera, Mukunda Ghadai, A Leelaveni
pp. 40–48 · DOI: 10.5530/pres.20260209 · Published Oct-Dec 2026
Background The traditional understanding of plant-based medicine has been passed down through the ages and has been assimilated by various ethnic groups as ethnopharmacological knowledge. The present study focuses on the…
- Article
Daidzein Attenuates Allergic Asthma via NF-κB1 Downregulation and Cytokine Modulation: A Comprehensive Preclinical Evaluation
Ankita Haldankar, Niraj Vyawahare, Pavankumar Wankhade, Shubhangi Daswadkar, Kaveri Urade
pp. 49–64 · DOI: 10.5530/pres.20260241 · Published Oct-Dec 2026
Background Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and…
- Article
Phytochemical Profiling of Unripe Fruits of Ficus carica and Phyllanthus emblica Grown in West Bengal and Evaluation of their in vitro Antidiabetic and Anti-Inflammatory Activity
Swarnabha Mukherjee, Neha Mondal, Shreya Mondal, Gargi Banerjee, Tushar Adhikari
pp. 65–71 · DOI: 10.5530/pres.20270039 · Published Oct-Dec 2027
Background Unripe fruits are promising sources of nutrition in the daily diet, which have gained attention for their rich phytochemical profile and associated health benefits. Objectives The present study aimed to profil…
- Article
High Performance Thin Layer Chromatography (HPTLC) Methods for Simultaneous Estimation and Quantification of Vasicine, Gallic acid, Piperine and Pterostilbene from Two Ayurvedic Formulations and Herbal Extracts
Sachin Baburao Mulik, Sanjay Uttamrao Nipanikar, Priyanka Patil, Ankita Kasabe, Pravin Surwade
pp. 72–85 · DOI: 10.5530/pres.20260009 · Published Oct-Dec 2026
Background High Performance Thin Layer Chromatography (HPTLC) is an advanced analytical technique used for the identification and quantification of marker compounds in Ayurvedic formulations. Aims and Objectives The purp…
- Article
Pharmacognostical Standardization of Leaf and Stem Bark of Elaeodendron glaucum (Rottb.) Pers.- An Important Ethno-Medicinal Plant
Ramanjaneyulu Kanugala, Goli Penchala Pratap, Mohd Kashif Husain, Maramreddy Prathapa Reddy, Sidama Gopal, Mohammad Zakir, Gudivada Sudarsanam
pp. 86–99 · DOI: 10.5530/pres.20260070 · Published Oct-Dec 2026
Background Elaeodendron glaucum (Rottb.) Pers. is an essential ethnomedicinal plant belonging to Celastraceae used in the treatment of various ailments like antidotes for snake bites, dog bites, wounds and cracks, dysuri…
- Article
GC-MS Analysis of Bioactive Phytocompounds in Polyherbal Formulation Extracted Ointment Used in the Management of Wound Healing
Neha Suresh Palase, Santosh Y Mudakappagol
pp. 100–115 · DOI: 10.5530/pres.20260075 · Published Oct-Dec 2026
Background The scientific validation of traditional as well as proprietary Ayurvedic formulations is crucial for the purpose of healing of wound in chronic non healing wounds. Polyherbal Formulation Extracted Ointment, a…
- Article
Anticancer Potential of Tephrosia maxima: Inhibition of Cell Viability and Colony Forming Ability in Oral Squamous Cell Carcinoma Cell Lines
Amitha Mohan, Anoop Kumar, Abilasha Ramasubramanian
pp. 116–123 · DOI: 10.5530/pres.20270078 · Published Oct-Dec 2027
Introduction Oral Squamous Cell Carcinoma (OSCC) continues to be a significant global health challenge, especially in developing areas, where lifestyle associated risk factors increase its prevalence. Even with improveme…
- Article
Characterization and Chromatographic Evaluation of Shatapushpadi Lepa
Sushmita Sanjay Gengane, Anil Koralli, Pranjali Abhay Patil, Shreya Balasaheb Nikam
pp. 124–132 · DOI: 10.5530/pres.20270080 · Published Jan-Mar 2027
Background Shatapushpadi Lepa is a traditional external application specified in Ayurveda. The composition that is advised for Vata-dominant inflammatory joint diseases. To determine quality, and therapeutic effectivenes…
- Article
Taxonomic Characterization and Ethnobotanical Insights of Bergenia ciliata Used by Hakeems in the Kashmir Himalaya
Sabira Nissar, Tahir Mushtaq, P. A. Sofi, Ishtiyak Ahmad Peerzada, Meraj U Din Dar, A. R. Malik, Ummar Atta, Moamenla Jamir
pp. 133–140 · DOI: 10.5530/pres.20270104 · Published Jan-Mar 2026
Background The Kashmir Himalaya is known for its rich diversity of medicinal plants that support traditional healthcare systems, where indigenous knowledge plays a vital role in disease management. Among these, Bergenia …
- Article
Comparative In vitro Evaluation of Chemical and Herbal Antimicrobial Agents for Surface Decontamination: A Pharmaceutical Perspective
Preethi Vem, Sathwika Rao Nadipelli, Daneswari Velagala, Vaishnavi Julakanti, Shivani Thoom, Deekshita Kavali Venugopal, Naseemoon Shaik
pp. 141–145 · DOI: 10.5530/pres.20270107 · Published Jan-Mar 2026
Background Maintenance of asepsis is essential for successful endodontic therapy. Gutta-percha cones are susceptible to microbial contamination during handling and storage, and their thermoplastic nature precludes heat s…
- Article
GC-MS Analysis and Quality Evaluation of Dashmoola Kashaya
Shreya Balasaheb Nikam, Rajashekhar Sanapeti, Anil Koralli, Shubham Deepak Anuse, Sushmita Sanjay Gengane
pp. 146–153 · DOI: 10.5530/pres.20270108 · Published Jan-Mar 2026
Background Dashmoola Kashaya is ayurvedic polyherbal formulation prepared from roots of ten medicinal plants which are traditionally used in the management of disorders like inflammatory conditions, neuromuscular disorde…
- Article
Acute Toxicity Study of Novel Ayurvedic Formulation Siddha Shalmali Kalpa (Classical Shalmali malabarica formulation) in Wistar Rat in vivo Experimental Study
Pravin Kadappa Koparde, Mujahid Khan, Sheetal Pravin Koparde
pp. 154–161 · DOI: 10.5530/pres.20270075 · Published Jan-Mar 2026
Background Traditional Ayurvedic Herbal remedies have long been used to improve and revitalize reproductive health. Siddha Shalmali Kalpa (Classical Shalmali malabarica formulation) is one such formulation that has long …
- Article
A Study on the Pharmacognosy Materials of Ancient Traditional Medicine Prescriptions Used to Treat Bubonic Plague
Dagvadorj Tserendorj, Javkhlan Bold, Myagmardash Bazarragchaa, Darmaa Munkhdorj, Bayar Enkhbold, Bold Sharav
pp. 162–167 · DOI: 10.5530/pres.20270128 · Published Jan-Mar 2026
Background Ancient Mongolian doctors and scholar-monks identified diseases that were prevalent among Mongolians but were not described in Indian Ayurveda or Tibetan medicine. Based on the theory of wind, bile, and phlegm…
- Article
Comparative Analysis of Multi-Solvent Tinospora cordifolia Fresh and Dry Leaf Extract Using Advanced Analytical Approaches
KJ Sharmila, Nishalini Palani, Aarthy Sundaram, Santhiya Jayakumar
pp. 168–175 · DOI: 10.5530/pres.20270135 · Published Jan-Mar 2026
Background Tinospora cordifolia is used worldwide for its medicinal properties, but its bioactive phytoconstituents have been less explored. Objectives The fresh and dry leaf extracts of Tinospora cordifolia, a tradition…
- Article
Chemically Synthesized Urolithin-C Regulates Glucose Uptake in HepG2 Cells
Vani Manjappa Karadi, Manjula Mavathuru Venkatappa, Shivakumar Venkataramaiah, Sanjana Bai Shivaram Singh Mahendaranath Singh, Sushma Mohan, Ramesh Komalapura Lakshmaiah, Devaraja Sannaningaiah
pp. 176–184 · DOI: 10.5530/pres.20270138 · Published Jan-Mar 2026
Background In recent years, the prevalence of diabetes has increased dramatically worldwide. Although several drugs are available for its management, their severe cytotoxic effects have created a need for safer and more …
- Article
An Amalgamated in silico Approach to Screen Lipid Lowering Herbs towards Developing Antilipidemic Polyherbal Formulation
Vandana Tyagi, Namita Arora, Pankaj Arora
pp. 185–201 · DOI: 10.5530/pres.20270148 · Published Jan-Mar 2026
Background Atherosclerotic Cardiovascular Disease (ASCVD) is largely caused by hyperlipidemia, characterized by high cholesterol and triglyceride levels. Standard treatments like statins face limitations such as intolera…
- Article
GC-MS Phytochemical Profiling of Kaidarya Siddha Narikela Taila: Mechanistic Insights into Khalitya (Non-Specific Hairfall) Management
Sanyogeeta Ajay Dixit, Pankaj Sharma, Pradnya Prakash Hemke, Kashavva Veerabasayya Hiremath, Susmita Devgonda Shedbale, Namrata Bhagaje, Monika Yadav
pp. 202–214 · DOI: 10.5530/pres.20270141 · Published Jan-Mar 2026
Background Non-Specific Hairfall (NSHF), classified as Khalitya in Ayurveda (NAMC FA-3, ICD-11 TM2), has a significant global burden. Kaidarya siddha Narikela Taila (KNT) is a formulation prepared with Narikela Taila (Co…
- Article
In silico Assessment of Bioactive Compounds from Thaalisaathi Chooranam Targeting Alcohol Dehydrogenase in Alcoholic Liver Disease
Jinavani Jeevagan, Shaira Banu Ismail, Abarna Balasubramani, Priyadharshini Muniyasamy, Murugesan Sannasi, Sathish Adithya, Rajathinakaran, Madhavan Ramachandran
pp. 215–223 · DOI: 10.5530/pres.20270151 · Published Jan-Mar 2026
Background Alcoholic Liver Disease (ALD) is a major cause of cirrhosis-related morbidity and mortality, with limited therapies. Alcohol Dehydrogenase (ADH) plays a key role in ethanol metabolism and contributes to hepati…
- Article
Comparative Pharmaceutical and Analytical Evaluation of Shoolaharana Yoga: Bhavita Formulation Versus Hydroalcoholic Extract
Priya Darshani Koul, Yadevendra Yadav, Shuchi Mitra, Khemchand Sharma
pp. 224–232 · DOI: 10.5530/pres.20270153 · Published Jan-Mar 2026
Background Shoolaharana Yoga, described in Rasendra Sara Saṃgraha, is a classical Herbo-mineral formulation indicated for various types of pain. Ayurvedic pharmaceutical processes such as Shodhana (Purification) and Bhav…
- Article
Black Cumin (Nigella sativa) as a Natural Food Preservative: GC-MS Profiling and Antimicrobial Activity against Spoilage Microorganisms
Rashmi Shahi, Suvarna V. Chavannavar, N Bharath Kumar, M.S Yashaswini
pp. 233–242 · DOI: 10.5530/pres.20270158 · Published Jan-Mar 2026
Background Nigella sativa, also referred as black cumin and described as the miraculous herb, exhibits many medicinal and pharmacological properties. Objectives This research focused on the antimicrobial effectiveness of…
- Article
Knowledge, Attitudes, and Practices Regarding Ethnomedicinal Therapies in Oral Cancer Care: Insights from Healthcare Professionals with Reference to Thuja occidentalis
Saranya Ramsridhar, R Chandini, Vishnupriya Veeraraghavan, Khadijah Mohideen, Mutaz Ali-Hassan, Murali Balasubramaniam
pp. 243–251 · DOI: 10.5530/pres.20270167 · Published Jan-Mar 2026
Background Oral Squamous Cell Carcinoma (OSCC) remains a major global health challenge despite advances in conventional therapies. Growing interest in Complementary and Alternative Medicine (CAM) has heightened attention…
- Article
Phytochemical Profiling and Bioactivity Assessment of Traditional Medicinal Plants as Innovative Therapeutics for Wound Care Applications
Prabhavati Shinde, Shraddha Jaiswal, Vidya Tale, Shobha Khilari
pp. 252–263 · DOI: 10.5530/pres.20270169 · Published Jan-Mar 2026
Background The worldwide healthcare system faces significant challenges due to prevalence of chronic wounds worsen by antimicrobial resistant bacteria and polymicrobial biofilm. Objectives This research aims to unravel a…
- Article
Tamarindus indica L. Seed Hydroalcoholic Extract as a Natural Inhibitor for Urolithiasis: Evidence from in vitro and in vivo Studies
Ankita Ghanshyam Yelne, Vaibhav Mukund Shinde
pp. 264–273 · DOI: 10.5530/pres.20270113 · Published Jan-Mar 2026
Background Urolithiasis remains a recurrent condition that affects patients’ quality of life and causes significant mortality. Once common in Afro-Asian regions, its prevalence is rising in India and other tropical count…
- Article
Phytochemical Profiling and Inhibitory Impact of Piper nigrum and Syzygium aromaticum Extracts Targeting GH13 Family Amylases
Syeda Tayyaba Asif, Mohtasheem Ul Hassan, Shah Ali Ul Qader, Madiha Jamshed
pp. 274–281 · DOI: 10.5530/pres.20270171 · Published Jan-Mar 2026
Background Inhibition α-amylase have been reportedly providing a novel way in diabetes and obesity management. Purpose Research for the last decade has outlined on broad range of health beneficial of various condiments a…
- Article
Deep Eutectic Solvent as Green Alternative Solvents for Polygodial Extraction with Validated HPLC-UV Analysis and Evaluation of their Bioactivities
Adelina Simamora, Adit Santoso, Margretha Margretha, Kris Herawan Timotius
pp. 282–292 · DOI: 10.5530/pres.20270179 · Published Jan-Mar 2026
Introduction Akway (Tasmannia piperita), a native Papua plant is known for its benefits as stamina enhancer, antimicrobial, and antioxidant agents, which can be associated to polygodial, its marker compound. Green altern…
- Article
Development and Quality Assessment of Poshakriti: A Gluten-Free, Multipurpose, Multigrain, Nutritional Flour
pp. 293–299 · DOI: 10.5530/pres.20270182 · Published Jan-Mar 2026
Background Growing awareness of the health-nutrition interface and demand for convenient yet wholesome foods is rising. Traditional Indian diets, influenced by Ayurvedic principles, emphasize balanced combinations of cer…
- Article
Elucidating the role of Shatapushpa (Anethum graveolens L.) in Rheumatoid Arthritis through In vitro and In silico Analysis
Anil Koralli, Rashmi Motnalli, Kshama Mutalik, V Sri Venkata Krishnan
pp. 300–308 · DOI: 10.5530/pres.20270184 · Published Jan-Mar 2026
Introduction Day by day the prevalence of the diseases are increasing throughout the globe. One such disease that is having increase in incidence is Rheumatoid Arthritis (RA). With the rise in the occurrence there is nee…
- Article
Camellia sinensis Extract Mediated Synthesis of Fe3O4 Magnetic Nanoparticles for pH-Responsive Targeted Breast Cancer Therapy
M B Balaji, Gulipalli Pallavi, M U Imeiya, G S R Kedari, S Vimal, T S Mohamed Saleem
pp. 309–318 · DOI: 10.5530/pres.20270194 · Published Jan-Mar 2027
Objectives One challenge in treating breast cancer is that there are not enough drug delivery systems that can both target tumors specifically and have their own pharmacological effects. Materials and Methods This study …
- Article
Metabolomics Insight into PN01 and SA02: Anticancer Efficacy and Antidiabetic Enzyme Inhibition
Syeda Tayyaba Asif, Mohtasheem Ul Hassan, Shah Ali Ul Qader, Madiha Jamshed
pp. 319–328 · DOI: 10.5530/pres.20270197 · Published Jan-Mar 2026
Background Cancer is a major global health problem, with nearly 10 million deaths recorded in 2020. Approximately 30% of cancers in low- and lower-middle-income nations stem from infectious agents like Human Papillomavir…
- Article
Identification of Potential Plant-Based Bioactive Compounds as α-Synuclein Targets via Molecular Docking and Molecular Dynamics Simulations
Nivetha Rajendiran, Kannan Muthu, Gowdham Manivel, Ethirajan Sukumar, Senthilkumar Sivanesan
pp. 329–337 · DOI: 10.5530/pres.20270200 · Published Jan-Mar 2026
Introduction Parkinson’s Disease (PD) is a distressing neurodegenerative ailment that involves the demise of neurons present in dopaminergic system and continuous progression of α-synuclein into amyloid fibrils. Combatin…
- Article
Comparative GC-MS Profiling of n-Hexane Extracts from the Heartwood and Small Branches of Pterocarpus santalinus Linn.f.
Anju Sonkar, Om Prakash Rout, Pravin Kumar Joshi, Akhil Kumar Agrawal, Arun Kumar Singh Parihar, Nagendra Singh Chauhan, Chandan Sahu
pp. 338–347 · DOI: 10.5530/pres.20270202 · Published Jan-Mar 2026
Background Pterocarpus santalinus Linn.f. (Red Sandalwood) is an important medicinal plant known for its diverse bio active compounds. Evaluation of its phytoconstituents is essential for ensuring its therapeutic potenti…
- Article
Anticancer Effects of Schinus molle-Synthesized Iron Nanoparticles in Human Hela Cervical Cancer Cells
Pavithra Ramamoorthy, K M Ruban Chakravarthy, S Logeshwaran, S Vimal, T S Mohamed Saleem
pp. 355–8 · DOI: 10.5530/pres.20270206 · Published Jan-Mar 2027
Objectives Green development of iron nanoparticles by plant derived extracts has collected important scientific attention due to their eco-friendly fabrication, cost-effectiveness, and enhanced biological activities. Mat…
- Article
Shenmai Injection Attenuates Pressure Overload-Induced Cardiac Hypertrophy by Modulating HRAS
Xiaojuan Zhou, Xueying Xu, Xiaolu Hou, Mulan Wang, Tian Liang, Peiqiang Shen, Shujing Zhang, Han Wang, Yingchao Wang, Qinqin Zhao
pp. 356–369 · DOI: 10.5530/pres.20270208 · Published Jan-Mar 2026
Background/Objectives Pressure overload-induced cardiac hypertrophy is a critical pathological precursor in the development of heart failure. Shenmai Injection (SMI) is widely used to treat cardiovascular diseases. Howev…
- Article
Green-Synthesized Tribulus terrestris-Mediated CuO Nanoparticle-Loaded CS/PVA Hydrogels: A Multifunctional Platform for Cancer Therapy and Antidiabetic Applications
Akshaya Viswanathan, P V Avinash, G S R Kedari, S Vimal, T S Mohamed Saleem
pp. 370–377 · DOI: 10.5530/pres.20270207 · Published Jan-Mar 2027
Objectives In this work, we report on the preparation of CuO nanoparticles using extract from Tribulus terrestris as a natural reducing and stabilizing agent, followed by the loading of the nanoparticles into the Chitosa…
- Article
Comparative Structural and Biophysical Profiling of Dengue Virus NS5 Methyltransferase Identifies DENV-4 as a Prioritized Antiviral Target
Afaf Salim Alwabli, Ghadeer Fareed Bukhari
pp. 378–386 · DOI: 10.5530/pres.20260215 · Published Oct-Dec 2026
Background The NS5 Methyltransferase (MTase) domain is essential for the capping and replication of dengue virus RNA and for the virus's evasion of the host immune response, making it a promising antiviral target. Purpos…
- Article
Integrated Phytochemical and Chromatographic Analysis for Detection of Adulteration in Terminalia chebula Fruit Rind Powder
Likitha Shankarappa, Mamatha A Rao, M Devendra Reddy, NS Prakash, Surendra Chennu
pp. 387–397 · DOI: 10.5530/pres.20270186 · Published Jan-Mar 2026
Background Terminalia chebula Retz. is a well-recognized medicinal plant widely used in the Ayurveda and Siddha systems of medicine, wherein the fruit rind is designated as the official therapeutic component. Admixture o…
- Article
Isolation and Characterization of Saponins from Asparagus racemosus: A HPTLC and LC-MS Study
Rajni Mishra, Ashish Singhai, Mukesh Singh Sikarwar
pp. 406–412 · DOI: 10.5530/pres.20270277 · Published Jan-Mar 2026
Background Shatavari or Asparagus racemosus Wild. Family Liliaceae is an important therapeutic herb in the health care system. It contains a sapogenin content which is a precursor of many pharmacologically active steroid…
- Article
Modulation of KEAP1/NRF2-Regulated Anticancer Chemopreventive Signalling Pathways by Anacardic Acid in MCF7-ARE Human Breast Cancer Cells
Sangita Panda, Enketeswara Subudhi, Anand Bhaskar, Dishant Maniar, Vivek Basudkar, Aswathi Biju, Siddharth Modi, Dilip Mehta, Sujit Nair
pp. 413–429 · DOI: 10.5530/pres.20270159 · Published Jan-Mar 2026
Background Breast cancer is the most diagnosed cancer worldwide, with an escalating burden over the past decades. Anacardic Acid (AA), a phenolic lipid extracted from cashew nutshell, displays diverse therapeutic propert…